85580C

Sigma

 

LONG®R3 IGF-I human

media grade, recombinant, expressed in Escherichia coli, lyophilized powder

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Description

ApplicationLONG R3 IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. It is more biologically potent in vitro than either insulin or native IGF-I and has been shown to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. All cells that have a growth response to insulin in cell culture have the potential to respond to LONG R3 IGF-I. LONG R3 IGF-I is effective in commercially relevant cell types including CHO, PER.C6™ and HEK 293. Hybridomas and fibroblasts have also been shown to respond to LONG R3 IGF-I.

LONG R3 IGF-I is produced in a patented E. coli expression system without the use of animal-derived components.
 LONG®R3IGF-I is a recombinant analog of human insulin-like growth factor (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. LONG®R3IGF-I is more biologically potent in vitro than either insulin or native IGF-I and has been documented to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. LONG®R3IGF-I is effective in any cell that contains type I IGF receptors, including most Chinese Hamster Ovary (CHO) lines, hybridomas and fibroblasts. LONG®R3IGF-I is produced in a patented E. coli expression systems free of animal-derived components.
Other NotesThis product should be purchased through SAFC Biosciences by contacting their customer service at the following phone numbers: in North America, 1-800-255-6032 or +1 913-469-5580; in Europe, +44 (0) 1264-333311; and in Asia-Pacific (including Australia and Japan), +61 (0)3-9362-4500 or 1-800-200-404.
Legal InformationAvailable in USA, Canada, and Europe. Please check with your local supplier regarding availability and restrictions in other countries.
 LONG is a registered trademark of Novozymes Biopharma AU

Properties

recombinantexpressed in Escherichia coli
grademedia grade
formlyophilized powder
availabilitynot available in Japan
storage temp.2-8°C

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany3